Enabling Biocatalysis

Synthesizing the impossible

Altozyme's proprietary cofactor regeneration platform unlocks a class of enzymatic chemistry that has been inaccessible at industrial scale — until now.

Fragrance Ingredients Chiral Pharmaceuticals and Precursors Deuterated Compounds
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What we do

A platform for chemistry that wasn't possible before

One third of all enzymes require cofactors — molecules like NAD⁺ and NADP⁺ — to function. At $25,000–$230,000 per mole, these cofactors are hard to scale. Existing regeneration methods produce inhibitory byproducts that defeat the purpose.

Altozyme has developed a novel route for regeneration that allows indefinite cofactor recycling, without byproducts and contamination.

This unlocks a broad class of stereoselective enzymatic chemistry — enabling synthesis of chiral and deuterated molecules that are currently inaccessible or prohibitively expensive to make.

Rx
Chiral Pharmaceutical Precursors
60% of new small-molecule drugs require chiral precursors. Cofactor regeneration is the bottleneck in enzymatic routes. Our platform removes it — opening a $70B market to biocatalytic synthesis.
²H
Deuterated Compounds
Economical deuteration using cheap D₂O sources — inaccessible by other enzymatic methods. Applications in metabolically stable pharmaceuticals and research reagents.

Let's build something impossible

We're in active conversations with fragrance houses, CDMOs, and research partners. If you work in specialty chemicals, fragrance R&D, or pharmaceutical process chemistry — we'd like to hear from you.

jacybau@gmail.com